Partners in Leaky Gut Syndrome: Intestinal Dysbiosis and Autoimmunity
نویسندگان
چکیده
منابع مشابه
Leaky Gut Syndrome
The chances of being diagnosed with Leaky Gut Syndrome are pretty remote. It does not even occur to many doctors to check for the condition. A further complication is that gut distress often manifests as disease in other parts of the body. Leaky Gut Syndrome is one of the most misunderstood concepts in modern medicine. This condition is associated with an abnormal increase in the permeability o...
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Objective(s): Zonula occludens proteins (ZO-1 and ZO-2) are important intracellular tight junction (TJ)-associated proteins that link the cell cytoskeleton to the trans-membrane TJ proteins. Destruction of TJ proteins is called the “leaky gut syndrome” and has been observed in some of the gastrointestinal diseases such as the inflammatory bowel disease (IBD). So, ther...
متن کاملWhat is Leaky Gut Syndrome?
Leaky Gut Syndrome is the name given to a very common health disorder in which the intestinal lining is more permeable than normal. The abnormally large spaces present between the cells of the gut wall allow the entry of toxic material into the bloodstream that would, in healthier circumstances, be repelled and eliminated. The gut becomes “leaky” in the sense that bacteria, viruses, fungi, para...
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One of the most significant challenges of cell biology is to understand how each type of cell copes with its specific workload without suffering damage. Among the most intriguing questions concerns intestinal epithelial cells in mammals; these cells act as a barrier between the internally protected region and the external environment that is exposed constantly to food and microbes. A major proc...
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There is now evidence that the pathophysiology of chronic fatigue syndrome (CFS) is related to inflammation and oxidative & nitrosative stress (IO&NS) with a) signs of immune activation and a suppression of ex vivo cellular immune responses; and b) damage to membrane lipids, functional proteins and DNA by O&NS. The above disorders are mediated by intracellular inflammation as indicated by an in...
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ژورنال
عنوان ژورنال: Frontiers in Immunology
سال: 2021
ISSN: 1664-3224
DOI: 10.3389/fimmu.2021.673708